La Enfermedad Celíaca Enteropatía Inmune.

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Celiac Disease - From Pathophysiology to Advanced Therapies

Edited by Peter Kruzliak and Govind Bhagat, ISBN 978-953-51-0684-5, Hard cover, 184 pages, Publisher: InTech, Published: July 19, 2012 under CC BY 3.0 license, in subject GastroenterologyDOI: 10.5772/1080

Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye and barley) in genetically susceptible individuals. CD can manifest itself with a previously unappreciated range of clinical presentations, including the typical malabsorption syndrome and a spectrum of symptoms potentially affecting any organ system. Since CD often presents in an atypical or even silent manner, many cases remain undiagnosed and carry the risk of long-term complications, including anemia and other hematological complications, osteoporosis, neurological complications or cancer. The high prevalence of the disease and its variety of clinical outcomes raise several interesting questions. This book covers most of the aforementioned controversial and yet unresolved topics by including the contributions of experts in CD.What the reader will surely find stimulating about this book is not only its exhaustive coverage of our current knowledge of CD, but also provocative new concepts in disease pathogenesis and treatment.

BOOK CONTENTS

• Chapter 1  Mucosal expression of claudins in children with celiac diseaseby Gabor Veres, Dorottya Nagy-Szakal, Hajnalka Győrffy, Kriszta Molnár,                                   Katalin Müller,    Mária Papp and András Arató
• Chapter 2  Antioxidant status of the celiac mucosa: implications for disease pathogenesisby Stojiljković, Jelena Kasapović, Snežana Pejić, Ljubica Gavrilović,                                         Nedeljko Radlović, Zorica Saičić and Snežana Pajović
• Chapter 3  Heat shock proteins (HSPs) in coeliac diseaseby Erna Sziksz, Leonóra Himer, Gabor Veres, Beáta Szebeni, András Arató,                                Tivadar Tulassay and Adam Vannay
• Chapter 4  Celiac disease and diabetes mellitus type 1.by Mieczyslaw Szalecki and Piotr Albrecht
• Chapter 5  Hematologic manifestations of celiac diseaseby Peter Kruzliak
• Chapter 6  Multiple Sclerosis and Celiac Diseaseby Carlos Hernández-Lahoz and Luis Rodrigo
• Chapter 7  Sensitive detection of cereal fractions that are toxic to celiac disease patients by using monoclonal antibodies to a main immunogenic gluten peptideby Carolina Sousa, Ana Real, Mª De Lourdes Moreno and Isabel Comino
• Chapter 8  Enzyme Therapy for Coeliac Disease: Is It Ready For Prime Time?by Cornell and Teodor Stelmasiak
• Chapter 9  Principles and Strategies for Monitoring Individuals with Celiac Diseaseby Mohsin Rashid
• Chapter 10  On treatment outcomes in coeliac disease diagnosed in adulthoodby Claes Hallert
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